The epidemic of chronic diseases, a better understanding of the underlying mechanisms and causes as well as technological advancements are transforming medicine from a reactive to a pro-active and preventive discipline.
Modern biology and medicine provides deeper insights into disease mechanisms, makes blood a diagnostic window for viewing health and disease for the individual and generates metrics for assessing wellness.
P4 is an approach to make medicine more Predictive, Preventive, Personalised and Participatory. Its two major objectives are to quantify wellness and predict and prevent disease.
P4 medicine aims to be able to detect and treat perturbations in healthy individuals long before disease symptoms appear, thus optimizing the wellness of individuals and avoiding disease. P4 medicine represents a move away from models of reacting to illness to maintaining health across the lifespan.
It would mean that data collected through diagnostic tests, health ‘apps’, and other tools can help people to understand risk factors and counteract them.
Many academic institutions and experts see P4 medicine as an important area for research and development, and have identified positive steps and barriers to progress in this area. Moving to a P4 model will involve patients and stakeholders from across the healthcare sector working together.
P4 medicine aims to 1) improve health care, 2) reduce the cost of health care, and 3) stimulate innovation and new company creation. Health care is not the only subject that can benefit from such integrative, cross-disciplinary, and systems-driven platforms and cultures. Many other challenges affecting the modern world, such as energy, environment, nutrition, and agriculture can be transformed by using such an integrated and systems-driven approach.
P4 medicine is the convergence of systems medicine, digital technologies and consumer-driven healthcare.
- P4 medicine is the clinical face of systems medicine.
- P4 medicine will make blood a diagnostic window for viewing health and disease for the individual.
- P4 medicine will provide new approaches to drug target discovery.
- P4 medicine will drive profound economic, policy and social changes.
P4 medicine aims to revolutionize the practice of healthcare in the coming decades. Today, medicine is largely reactive. It waits until a person is sick and then treats a disease, with varying levels of success. The revolution will emerge from the convergence of systems biology and the digital revolution’s ability to create consumer devices, generate and analyze “big data” sets and deploy this information through business and social networks.